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Home/Compounds/Pharmaceutical Intermediate/(R)-NODAGA-tris(t-Bu ester)
C27H49N3O8
543.7 g/mol
Pharmaceutical Intermediate

(R)-NODAGA-tris(t-Bu ester)

CAS1252799-47-5
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

(R)-NODAGA-tris(t-Bu ester) is a protected chelating agent intermediate used in bioconjugation. It features a triazacyclononane macrocycle with tert-butyl ester protecting groups and a free carboxylic acid, designed for subsequent activation and conjugation to biomolecules.

Intermediate for the synthesis of bifunctional chelatorsBuilding block for radiopharmaceutical precursorsReagent for bioconjugation chemistry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 1.00

DOTA-GA(tBu)4

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ReferenceSame Category

(S)-2-Amino-1,1,1-trifluoropropane hydrochloride

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Referencestereoisomer of

(S)-4-(4,7-Bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7-triazonan-1-yl)-5-(tert-butoxy)-5-oxopentanoic acid

CAS438553-50-5

research compound

Referencesame scaffold

NOTA-bis(tBu)ester

CAS1161415-28-6

research compound

Referencesame scaffold

1,4,7-triazonane

CAS4730-54-5

research compound

Identifiers
IUPAC Name

(4R)-4-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7-triazonan-1-yl]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid

InChIKey

ADHGPCATMVZKLP-HXUWFJFHSA-N

SMILES

CC(C)(C)OC(=O)CN1CCN(CCN(CC1)[C@H](CCC(=O)O)C(=O)OC(C)(C)C)CC(=O)OC(C)(C)C

Synonyms (5)
  • (R)-NODA-GA(tBu)3
  • (R)-NODAGA-tris(t-Bu ester)
  • (R)-NOTA-GA-(COOt-Bu)3