C24H27NO5
409.5 g/mol
Research ReagentWarning
(2S,4R)-4-(tert-butoxy)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-2-carboxylic acid
CAS122996-47-8EC857-376-1
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound
This compound is an Fmoc-protected amino acid building block specifically featuring a tert-butoxy-protected hydroxyproline residue. It is primarily used in solid-phase peptide synthesis as a protected precursor for incorporating modified proline derivatives into synthetic peptides.
Solid-phase peptide synthesisResearch reagent for peptide chemistry
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.82
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SimilarStructure SimilarSimilarity 0.81
(2S,4R)-4-tert-butoxy-1-(9H-fluoren-9-ylmethoxycarbonyl)piperidine-2-carboxylic acid
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pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.81
(2S,4S)-4-tert-butoxy-1-(9H-fluoren-9-ylmethoxycarbonyl)piperidine-2-carboxylic acid
CAS3020708-19-1
pharmaceutical intermediate
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Related Reading
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S,4R)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidine-2-carboxylic acid
InChIKey
WPBXBYOKQUEIDW-VFNWGFHPSA-N
SMILES
CC(C)(C)O[C@@H]1C[C@H](N(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O
Synonyms (15)
- Fmoc-D-Hyp(tBu)-OH
- Fmoc-Hyp(OtBu)OH
- Fmoc-Hyp(tBu)-OH
- Fmoc-L-Hyp(tBu)-OH
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