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Home/Compounds/API/Ifebemtinib
C28H28F4N6O4
588.6 g/mol
API

Ifebemtinib

CAS1227948-82-4
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Ifebemtinib is an orally bioavailable inhibitor of focal adhesion kinase (FAK/PTK2), a non-receptor cytoplasmic tyrosine kinase. It exhibits antineoplastic activity by competitively binding to ATP and blocking PTK2-mediated signaling, thereby inhibiting tumor cell migration, proliferation, invasion, and survival.

Pharmaceutical raw material for anticancer researchLaboratory reagent for focal adhesion kinase inhibition studiesCompound for investigating tumor cell signaling pathways

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

2-fluoro-5-methoxy-4-[[4-[(2-methyl-3-oxo-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-N-(1-methylpiperidin-4-yl)benzamide

InChIKey

ULMMVBPTWVRPSI-UHFFFAOYSA-N

SMILES

CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2F)NC3=NC=C(C(=N3)OC4=CC=CC5=C4C(=O)N(C5)C)C(F)(F)F)OC

Synonyms (8)
  • BI 853520
  • Ifebemtinib
  • US8846689, 69