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Home/Compounds/Pharmaceutical Intermediate/Phosphine oxide, [(2R)-2,3-dimethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-
C24H37O2PSi
416.6 g/mol
Pharmaceutical Intermediate

Phosphine oxide, [(2R)-2,3-dimethyl-3-[(triethylsilyl)oxy]butyl]diphenyl-

CAS1227926-70-6
Category
Pharmaceutical Intermediate
Compound Class
Organometallic
Primary Use
Pharmaceutical Intermediate

This compound is a phosphorus-containing organosilicon intermediate used in the synthesis of paricalcitol, a pharmaceutical active ingredient. It features a triethylsilyl protective group and a diphenylphosphoryl moiety, contributing to its role in specialized organic synthesis.

Pharmaceutical intermediate for paricalcitol manufacturingReagent in organic synthesis of vitamin D analogs

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

[(3R)-4-diphenylphosphoryl-2,3-dimethylbutan-2-yl]oxy-triethylsilane

InChIKey

MIKIXTFPADAALY-NRFANRHFSA-N

SMILES

CC[Si](CC)(CC)OC(C)(C)[C@@H](C)CP(=O)(C1=CC=CC=C1)C2=CC=CC=C2

Synonyms (8)

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