Home/Compounds/Research Reagent/(S)-N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-C-ALPHA-METHYL-2,6-DIFLUOROPHENYLALANINE
C25H21F2NO4
437.4 g/mol
Research ReagentWarning
(S)-N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-C-ALPHA-METHYL-2,6-DIFLUOROPHENYLALANINE
CAS1223105-51-8EC835-658-5
Category
Research Reagent
Compound Class
Amide
Primary Use
Research Compound
This compound is an Fmoc-protected, alpha-methylated derivative of 2,6-difluorophenylalanine, commonly used as a building block in solid-phase peptide synthesis. Its structure incorporates a fluorenylmethoxycarbonyl (Fmoc) group for temporary amine protection, enabling the stepwise assembly of peptides containing a sterically hindered, fluorinated amino acid residue.
Building block for synthesizing modified peptides with enhanced metabolic stabilityResearch reagent for introducing fluorinated amino acid residues into peptide sequences
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing or supplying this compound?
List your inventory or post a purchase request
CAS 1223105-51-8
Related Compounds
SimilarStructure SimilarSimilarity 0.80
FMoc-alpha-Me-D-Phe(2-F)-OH
CAS1315449-93-4
pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.80
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-fluorophenyl)-2-methylpropanoic acid
CAS1172127-44-4
research compound
ApplicationSame Use
Fmoc-L-tert-leucine
CAS132684-60-7
research compound
ApplicationSame Use
N-Fmoc-L-Glutamine
CAS71989-20-3
research compound
ApplicationSame Use
N-fmoc-L-norleucine
CAS77284-32-3
research compound
ApplicationSame Use
Fmoc-D-proline
CAS101555-62-8
research compound
ReferenceSame Category
Reactive Red 31
CAS12237-00-2
research compound
ReferenceSame Category
(4-(benzyloxy)-3,5-difluorophenyl)methanol
CAS1224103-99-4
research compound
Safety Reference
Warning
H361Suspected of damaging fertility or the unborn child
Identifiers
IUPAC Name
(2S)-3-(2,6-difluorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methylpropanoic acid
InChIKey
MRIVYBRWULFPFJ-VWLOTQADSA-N
SMILES
C[C@](CC1=C(C=CC=C1F)F)(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Synonyms (12)
- FMoc-|A-Me-Phe(2,6-DiF)-OH
- Fmoc-alpha-Me-Phe(2,6-DiF)-OH