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Home/Compounds/Pharmaceutical Intermediate/2'-deoxy-3'-O-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-Cytidine
C17H16N4O6
372.3 g/mol
Pharmaceutical Intermediate

2'-deoxy-3'-O-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-Cytidine

CAS1220515-69-4
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a modified nucleoside protected with a phthalimide group, used as a building block in the synthesis of oligonucleotides. It features a cytosine base attached to a modified sugar ring, with the 5'-hydroxyl group masked by the phthalimide moiety for selective deprotection during solid-phase synthesis.

building block for oligonucleotide synthesisintermediate for modified nucleic acid production

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 1220515-69-4

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Identifiers
IUPAC Name

2-[(2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl]oxyisoindole-1,3-dione

InChIKey

GSLQDLDOBMUSCB-OUCADQQQSA-N

SMILES

C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)ON3C(=O)C4=CC=CC=C4C3=O

Synonyms (2)

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