C24H30ClNO3
416 g/mol
APIDanger
Donepezil hydrochloride
CAS120011-70-3
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Donepezil hydrochloride is a piperidine derivative salt that acts as a reversible inhibitor of acetylcholinesterase, thereby increasing acetylcholine activity. It is primarily investigated for its neurocognitive-enhancing properties and is studied in the context of Alzheimer's disease and other cognitive impairments.
Pharmaceutical raw material for neurocognitive researchCompound used in acetylcholinesterase inhibition studiesLaboratory reagent for dementia-related investigations
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 120011-70-3
Related Compounds
StrongSame Parent
Donepezil
CAS120014-06-4
pharmaceutical raw material
StrongSame Parent
Donepezil hydrochloride monohydrate
CAS884740-09-4
pharmaceutical raw material
StrongSame Parent
Petrolite E 2020
CAS110119-84-1
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.72
1-Benzyl-4-[(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)methyl]piperidine--hydrogen chloride (1/1)
CAS1034439-57-0
pharmaceutical raw material
ReferenceSame Category
CHEMBL434811
CAS120012-04-6
pharmaceutical raw material
ReferenceSame Category
Dehydrodeoxy donepezil
CAS120013-45-8
pharmaceutical raw material
ReferenceSame Category
Rac (cis/trans) Donepezil N-Oxide
CAS120013-84-5
pharmaceutical raw material
ReferenceSame Category
1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine
CAS120014-07-5
pharmaceutical raw material
Safety Reference
Danger
H300Fatal if swallowed
H301Toxic if swallowed
H319Causes serious eye irritation
Identifiers
IUPAC Name
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride
InChIKey
XWAIAVWHZJNZQQ-UHFFFAOYSA-N
SMILES
COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl
Synonyms (45)
- BNAG
- E-2020
- E-2022
- Donepezil hydrochloride (JP18/USP)
- 120011-70-3 (HCl)
- Aricept
- Aricept (TN)
- Aricept D
- Aricept Evess
- Aricept ODT
- Donepezil HCl
- Donepezil HCl (Aricept)
- Donepezil Hydrochloride 10mg
- Donepezil Hydrochloride 5 mg
- Donepezil Hyrochloride
- Donepezil Hyrochloride 5mg
- Donepezil hydrochloride
- Donepezil hydrochloride CRS
- E 2020 (pharmaceutical)
- E2020;E-2020
- Eranz
- Memac
- Memorit