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Home/Compounds/API/Donepezil hydrochloride
C24H30ClNO3
416 g/mol
APIDanger

Donepezil hydrochloride

CAS120011-70-3
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Donepezil hydrochloride is a piperidine derivative salt that acts as a reversible inhibitor of acetylcholinesterase, thereby increasing acetylcholine activity. It is primarily investigated for its neurocognitive-enhancing properties and is studied in the context of Alzheimer's disease and other cognitive impairments.

Pharmaceutical raw material for neurocognitive researchCompound used in acetylcholinesterase inhibition studiesLaboratory reagent for dementia-related investigations

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Donepezil

CAS120014-06-4

pharmaceutical raw material

StrongSame Parent

Donepezil hydrochloride monohydrate

CAS884740-09-4

pharmaceutical raw material

StrongSame Parent

Petrolite E 2020

CAS110119-84-1

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.72

1-Benzyl-4-[(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)methyl]piperidine--hydrogen chloride (1/1)

CAS1034439-57-0

pharmaceutical raw material

ReferenceSame Category

CHEMBL434811

CAS120012-04-6

pharmaceutical raw material

ReferenceSame Category

Dehydrodeoxy donepezil

CAS120013-45-8

pharmaceutical raw material

ReferenceSame Category

Rac (cis/trans) Donepezil N-Oxide

CAS120013-84-5

pharmaceutical raw material

ReferenceSame Category

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine

CAS120014-07-5

pharmaceutical raw material

Safety Reference

Toxic
Toxic
Harmful
Harmful
Danger
H300Fatal if swallowed
H301Toxic if swallowed
H319Causes serious eye irritation

Customs Tariff Classification

The international HS code for Donepezil hydrochloride (CAS 120011-70-3) is 2933.39.

HS code (international, 6-digit)

2933.39

EU CN code (8-digit)

2933 39 99

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride

InChIKey

XWAIAVWHZJNZQQ-UHFFFAOYSA-N

SMILES

COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl

Synonyms (45)
  • BNAG
  • E-2020
  • E-2022
  • Donepezil hydrochloride (JP18/USP)
  • 120011-70-3 (HCl)
  • Aricept
  • Aricept (TN)
  • Aricept D
  • Aricept Evess
  • Aricept ODT
  • Donepezil HCl
  • Donepezil HCl (Aricept)
  • Donepezil Hydrochloride 10mg
  • Donepezil Hydrochloride 5 mg
  • Donepezil Hyrochloride
  • Donepezil Hyrochloride 5mg
  • Donepezil hydrochloride
  • Donepezil hydrochloride CRS
  • E 2020 (pharmaceutical)
  • E2020;E-2020
  • Eranz
  • Memac
  • Memorit

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