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Home/Compounds/Pharmaceutical Intermediate/(2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-((4-Dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy)-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane
C30H55NO10
589.8 g/mol
Pharmaceutical IntermediateWarning

(2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-((4-Dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy)-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane

CAS118058-74-5EC433-820-6
Category
Pharmaceutical Intermediate
Compound Class
Natural Product
Primary Use
Pharmaceutical Intermediate

This compound is a macrolide antibiotic derivative used primarily as a reference standard for clarithromycin. It serves as a pharmaceutical intermediate in the manufacturing and quality control of clarithromycin and related substances.

Reference standard for clarithromycin analysisPharmaceutical intermediate for clarithromycin production

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 118058-74-5

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Related Compounds

SimilarStructure SimilarSimilarity 0.78

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Safety Reference

Harmful
Harmful
Warning
H319Causes serious eye irritation
Identifiers
IUPAC Name

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-4,12,13-trihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

InChIKey

QTLYNHBYTKOXTE-FNAMOMDESA-N

SMILES

CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O)C)O[C@H]2[C@@H]([C@H](C[C@H](O2)C)N(C)C)O)(C)OC)C)C)O)(C)O

Synonyms (8)
  • Clarithromycin EP Impurity I; Clarithromycin USP Impurity I
  • De(cladinosyl) Clarithromycin
  • Decladinose