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Home/Compounds/Pharmaceutical Intermediate/Tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate
C10H18FNO3
219.25 g/mol
Pharmaceutical IntermediateWarning

(3S,4R)-1-Boc-3-fluoro-4-hydroxypiperidine

CAS1174020-40-6EC813-462-0
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a chiral, stereochemically defined piperidine derivative featuring a fluorine atom and a hydroxyl group on the ring. It is described in the chemical literature as a building block for medicinal chemistry, enabling the enantioselective synthesis of cis-3-fluoropiperidin-4-ol.

pharmaceutical building blockreagent for enantioselective synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

(3S,4R)-1-Boc-3-fluoro-4-hydroxypiperidine

CAS955028-88-3

pharmaceutical intermediate

ReferenceSame Category

Trans-tert-butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate

CAS1174020-45-1

pharmaceutical intermediate

ReferenceSame Category

(3R,4R)-tert-Butyl 3-fluoro-4-hydroxypyrrolidine-1-carboxylate

CAS1174020-50-8

pharmaceutical intermediate

ReferenceSame Category

(3S,4S)-tert-Butyl 3-fluoro-4-hydroxypyrrolidine-1-carboxylate

CAS1174020-51-9

pharmaceutical intermediate

Referencestereoisomer of

Tert-butyl (3R,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate

CAS1174020-42-8

pharmaceutical intermediate

Referencestereoisomer of

Rac-tert-butyl (3R,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate

CAS1174020-43-9

pharmaceutical intermediate

Referencestereoisomer of

Tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate

CAS1174020-44-0

pharmaceutical intermediate

Referencestereoisomer of

Tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate

CAS373604-28-5

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Identifiers
IUPAC Name

tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate

InChIKey

XRNLYXKYODGLMI-JGVFFNPUSA-N

SMILES

CC(C)(C)OC(=O)N1CC[C@H]([C@H](C1)F)O

Synonyms (12)

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