Home/Compounds/Pharmaceutical Intermediate/Tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate
C10H18FNO3
219.25 g/mol
Pharmaceutical IntermediateWarning
(3S,4R)-1-Boc-3-fluoro-4-hydroxypiperidine
CAS1174020-40-6EC813-462-0
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a chiral, stereochemically defined piperidine derivative featuring a fluorine atom and a hydroxyl group on the ring. It is described in the chemical literature as a building block for medicinal chemistry, enabling the enantioselective synthesis of cis-3-fluoropiperidin-4-ol.
pharmaceutical building blockreagent for enantioselective synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1174020-40-6
Related Compounds
StrongSame Parent
(3S,4R)-1-Boc-3-fluoro-4-hydroxypiperidine
CAS955028-88-3
pharmaceutical intermediate
ReferenceSame Category
Trans-tert-butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
CAS1174020-45-1
pharmaceutical intermediate
ReferenceSame Category
(3R,4R)-tert-Butyl 3-fluoro-4-hydroxypyrrolidine-1-carboxylate
CAS1174020-50-8
pharmaceutical intermediate
ReferenceSame Category
(3S,4S)-tert-Butyl 3-fluoro-4-hydroxypyrrolidine-1-carboxylate
CAS1174020-51-9
pharmaceutical intermediate
Referencestereoisomer of
Tert-butyl (3R,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate
CAS1174020-42-8
pharmaceutical intermediate
Referencestereoisomer of
Rac-tert-butyl (3R,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate
CAS1174020-43-9
pharmaceutical intermediate
Referencestereoisomer of
Tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate
CAS1174020-44-0
pharmaceutical intermediate
Referencestereoisomer of
Tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate
CAS373604-28-5
pharmaceutical intermediate
Safety Reference
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Identifiers
IUPAC Name
tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate
InChIKey
XRNLYXKYODGLMI-JGVFFNPUSA-N
SMILES
CC(C)(C)OC(=O)N1CC[C@H]([C@H](C1)F)O
Synonyms (12)
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