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Home/Compounds/API/Pevonedistat hydrochloride
C21H26ClN5O4S
480 g/mol
API

Pevonedistat Hydrochloride

CAS1160295-21-5
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Pevonedistat Hydrochloride is the hydrochloride salt form of pevonedistat, a small molecule inhibitor of Nedd8 activating enzyme (NAE). It is used in pharmaceutical research as a compound with potential antineoplastic activity, acting by inhibiting NAE and thereby affecting tumor cell proliferation and survival pathways.

Pharmaceutical raw material for NAE inhibitor researchAntineoplastic agent research compound

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

[(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamate;hydrochloride

InChIKey

HJKDNNXKYODZJI-BVMPOVDASA-N

SMILES

C1CC2=CC=CC=C2[C@H]1NC3=C4C=CN(C4=NC=N3)[C@@H]5C[C@H]([C@H](C5)O)COS(=O)(=O)N.Cl

Synonyms (12)
  • Pevonedistat hydrochloride (JAN/USAN)
  • MLN4924 HCl salt
  • MLN4924 hydrochloride
  • Pevonedistat HCl
  • Pevonedistat Hydrochloride