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Home/Compounds/Pharmaceutical Intermediate/N'-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-tetrahydrofuran-2-yl]purin-6-yl]-N,N-dimethyl-acetamidine
C44H55N8O6P
822.9 g/mol
Pharmaceutical Intermediate

N'-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-tetrahydrofuran-2-yl]purin-6-yl]-N,N-dimethyl-acetamidine

CAS115973-59-6
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a nucleoside phosphoramidite building block, a pharmaceutical intermediate used in the synthesis of oligonucleotides. It features a purine base with a protected hydroxyl group and a phosphoramidite moiety, making it a key reagent for solid-phase DNA/RNA synthesis.

Building block for oligonucleotide synthesisReagent for nucleic acid researchPharmaceutical intermediate for nucleoside analog manufacture

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 115973-59-6

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Related Compounds

SimilarStructure SimilarSimilarity 0.82

(Z)-N'-{9-[(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)oxolan-2-yl]-9H-purin-6-yl}-N,N-dimethylmethanimidamide

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research compound

SimilarStructure SimilarSimilarity 0.77

Ac-dA Phosphoramidite

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Identifiers
IUPAC Name

N'-[9-[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]-N,N-dimethylethanimidamide

InChIKey

PYXYDZCSILHILE-UHFFFAOYSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C(N=CN=C65)N=C(C)N(C)C

Synonyms (2)

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