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Home/Compounds/API/Tezacaftor
C26H27F3N2O6
520.5 g/mol
API

Tezacaftor

CAS1152311-62-0
Category
API
Compound Class
Other
Primary Use
Pharmaceutical Raw Material

Tezacaftor is a compound that functions as a CFTR (cystic fibrosis transmembrane conductance regulator) corrector, used in pharmaceutical manufacturing for cystic fibrosis research. It is a pharmaceutical raw material supplied to research and development organizations.

CFTR corrector for cystic fibrosis researchPharmaceutical raw material for drug development studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide

InChIKey

MJUVRTYWUMPBTR-MRXNPFEDSA-N

SMILES

CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F

Synonyms (21)
  • VX-661
  • Tezacaftor (USAN/INN)
  • Alyftrek
  • Kaftrio
  • SYMKEVI COMPONENT TEZACAFTOR
  • Symdeko
  • TRIKAFTA COMPONENT TEZACAFTOR
  • Tezacaftor
  • Tezacaftor (VX-661)
  • US10022352, Compound 315
  • example 315
  • tezacaftorum