Home/Compounds/API/(4R)-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one
C9H14F2N2O5
268.21 g/mol
APIWarning
Cedazuridine
CAS1141397-80-9
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Cedazuridine is a cytidine deaminase inhibitor used as a pharmaceutical raw material. It is combined with decitabine to prevent its degradation, thereby enabling oral administration for epigenetic therapy.
pharmaceutical raw material for oral decitabine combinationcytidine deaminase inhibitor in cancer research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1141397-80-9
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Referencesame scaffold
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Safety Reference
Warning
H302Harmful if swallowed
H332Harmful if inhaled
H341Suspected of causing genetic defects
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
(4R)-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one
InChIKey
VUDZSIYXZUYWSC-DBRKOABJSA-N
SMILES
C1CN(C(=O)N[C@@H]1O)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F
Synonyms (17)
- E-7727
- Cedazuridine (USAN/INN)
- CDA Inhibitor E7727
- Cedazuridina
- Cedazuridine
- Cedazuridine Impurity 2
- INQOVI COMPONENT CEDAZURIDINE
- cedazuridinum