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Home/Compounds/Pharmaceutical Intermediate/N-benzyloxycarbonylglycine
C10H11NO4
209.2 g/mol
Pharmaceutical IntermediateWarning

N-Benzyloxycarbonylglycine

CAS1138-80-3EC214-516-0
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

N-Benzyloxycarbonylglycine is a chemical compound used as a protecting group reagent in peptide synthesis. It is also the substrate for the enzyme N-benzyloxycarbonylglycine hydrolase, which cleaves it into benzyl alcohol, carbon dioxide, and glycine.

Protecting group reagent in peptide synthesisSubstrate for enzymatic hydrolysis studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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SimilarStructure SimilarSimilarity 0.75

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

2-(phenylmethoxycarbonylamino)acetic acid

InChIKey

CJUMAFVKTCBCJK-UHFFFAOYSA-N

SMILES

C1=CC=C(C=C1)COC(=O)NCC(=O)O

Synonyms (33)
  • (Cbz)gly
  • Benzyloxycarbonylglycine
  • Carbobenzoxyglycine
  • Carbobenzoxyl glycine
  • Carbobenzyloxyglycine
  • Cbz-Gly-OH
  • Cbz-Glycine
  • GLYCINE,N-BENZYLOXYCARBONYL
  • Glycine, N-benzyl ester
  • N-ALPHA-CBZ-GLYCINE
  • N-Benzyloxycarbonylglycine
  • N-CBZ-GLY-OH
  • N-CBZ-glycine
  • N-Carbobenzoxyglycine
  • N-Carbobenzyloxyglycine
  • N-Gly-OH
  • N-Z-Gly-OH
  • N-benzyloxycarbonyl-glycin
  • US9321743, Cbz-gly
  • Z-Gly
  • Z-Gly-OH
  • Z-Glycine
  • carbobenzoxy-glycin