This compound is a silyl-protected intermediate used in the synthesis of calcipotriol, a vitamin D analog. It features a complex stereochemistry defined by multiple chiral centers and tert-butyl(dimethyl)silyl (TBDMS) protecting groups.
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CAS 112849-27-1
[[(1a,3b,5E,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diyl]bis(oxy)]bis[(1,1-dimethylethyl)dimethylsilane]
research compound
(S)-2-((1R,3aS,7aR,E)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)propan-1-ol
pharmaceutical intermediate
(2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one
pharmaceutical intermediate
Fmoc-D-Aspartic acid beta-tert-butyl ester
pharmaceutical intermediate
2-Acetylamidomethyl-4-(4-fluorobenzyl)morpholine
pharmaceutical intermediate
2-Aminomethy-4-(4-fluorobenzyl)morpholine
pharmaceutical intermediate
O-Carbomethoxybenzyl sulfonamide
pharmaceutical intermediate
(5Z,7E,22E,24S)-24-cyclopropyl-1α,3β-bis(((1,1-dimethylethyl)dimethylsilyl)oxy)-9,10-secochola-5,7,10(19),22-tetraen-24-ol
pharmaceutical intermediate
(E,1S,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-1-cyclopropylpent-2-en-1-ol
DIMYHZDULFSWLS-YFSXTQNDSA-N
C[C@H](/C=C/[C@H](C1CC1)O)[C@H]2CC[C@@H]\3[C@@]2(CCC/C3=C\C=C\4/C[C@H](C[C@@H](C4=C)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)C