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Home/Compounds/Pharmaceutical Intermediate/N-(4,4'-Dimethoxytrityl)-8-bromoguanosine 2',3',5'-Triacetate
C37H36BrN5O10
790.6 g/mol
Pharmaceutical Intermediate

N-(4,4'-Dimethoxytrityl)-8-bromoguanosine 2',3',5'-Triacetate

CAS1096020-93-7
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a protected nucleoside used as an intermediate in oligonucleotide synthesis. It features multiple acetyl ester protective groups and a brominated purine base with a dimethoxytrityl (DMT) protecting group, which are typical for solid-phase RNA or DNA assembly.

Protected nucleoside for oligonucleotide synthesisPharmaceutical intermediate for research and manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

[(2R,3R,4R,5R)-3,4-diacetyloxy-5-[2-[[bis(4-methoxyphenyl)-phenylmethyl]amino]-8-bromo-6-oxo-1H-purin-9-yl]oxolan-2-yl]methyl acetate

InChIKey

DHIXZEUEBYPZHU-UTBAFCPYSA-N

SMILES

CC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C3=C(C(=O)NC(=N3)NC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)N=C2Br)OC(=O)C)OC(=O)C

Synonyms (5)

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