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Home/Compounds/Industrial Chemical/Tetrahydrofuran
C4H8O
72.11 g/mol
Industrial ChemicalDanger

Oxolane

CAS109-99-9EC203-726-8
Category
Industrial Chemical
Compound Class
Heterocycle
Primary Use
industrial solvent and chemical intermediate

Oxolane, also known as tetrahydrofuran (THF), is a colorless, water-miscible organic liquid with low viscosity. It is a cyclic ether widely used as an industrial solvent and chemical intermediate.

industrial solventchemical intermediate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Restricted or banned substances

Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.

Relevant lists:California Proposition 65

CAS 109-99-9

Related Compounds

StrongSame Parent

Borane—tetrahydrofuran complex

CAS14044-65-6

research compound

StrongSame Parent

Tetrachlorobis(tetrahydrofuran)zirconium

CAS21959-01-3

research compound

StrongSame Parent

Boron trifluoride tetrahydrofuran complex

CAS462-34-0

polymerization catalyst and semiconductor dopant

StrongStructure SimilarSimilarity 0.89

Tetrahydropyran

CAS142-68-7

industrial solvent and chemical intermediate

ApplicationSame Use

Tert-Amylbenzene

CAS2049-95-8

industrial solvent and chemical intermediate

ApplicationSame Use

1,3-Bis(trifluoromethyl)-benzene

CAS402-31-3

industrial solvent and chemical intermediate

ApplicationSame Use

Cycloheptanol

CAS502-41-0

industrial solvent and chemical intermediate

ApplicationSame Use

Cyclohexylbenzene

CAS827-52-1

industrial solvent and chemical intermediate

Safety Reference

Flammable
Flammable
Harmful
Harmful
Health Hazard
Health Hazard
Danger
H225Highly flammable liquid and vapour
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
H302Harmful if swallowed
H336May cause drowsiness or dizziness
H315Causes skin irritation
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H371May cause damage to organs
Regulatory Compliance2
  • California Proposition 65USRegulation
    Listed· listed since 2021-12-17Source
  • CN Catalogue of Hazardous ChemicalsCNRegulation
    Listed· listed since 2015-05-01Source

Customs Tariff Classification

The international HS code for Oxolane (CAS 109-99-9) is 2932.11.

HS code (international, 6-digit)

2932.11

EU CN code (8-digit)

2932 11 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

oxolane

InChIKey

WYURNTSHIVDZCO-UHFFFAOYSA-N

SMILES

C1CCOC1

Synonyms (76)
  • THF
  • 1,4-Epoxybutane
  • Agrisynth THF
  • Butane a,d-oxide
  • Butane, 1,4-epoxy-
  • Butane, alpha,delta-oxide
  • Butane,4-epoxy-
  • Butylene oxide
  • Cyclotetramethylene
  • Cyclotetramethylene oxide
  • Diethylene oxide
  • Dynasolve 150
  • Furan, tetrahydro-
  • Furanidine
  • Hydrofuran
  • Oxacyclopentane
  • Oxolane
  • THF (tetrahydrofuran)
  • Tetrahydrofuraan
  • Tetrahydrofuraan [Dutch]
  • Tetrahydrofuran ACS
  • Tetrahydrofuran SpS
  • Tetrahydrofuran Ultra LC-MS
  • Tetrahydrofuran unstabilised
  • Tetrahydrofuran(THF)
  • Tetrahydrofuran, Biograde
  • Tetrahydrofuran, UV
  • Tetrahydrofuran, anhydrous
  • Tetrahydrofuran, p.a.
  • Tetrahydrofurane
  • Tetrahydrofuranne
  • Tetrahydrofuranne [French]
  • Tetraidrofurano
  • Tetraidrofurano [Italian]
  • Tetramethylene oxide
  • terahydrofuran
  • terahydrofurane
  • terahyrofuran
  • tetrahydofuran
  • tetrahydofurane
  • tetrahydorfuran
  • tetrahydro-furan
  • tetrahydrofuran solvent
  • tetrahyrdofuran
  • tetrahyrofuran
  • tetraliydrofuran