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Home/Compounds/Pharmaceutical Intermediate/Dibenzyl N,N-diisopropylphosphoramidite
C20H28NO2P
345.4 g/mol
Pharmaceutical IntermediateWarning

Bis(benzyloxy)(diisopropylamino)phosphine

CAS108549-23-1
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

Bis(benzyloxy)(diisopropylamino)phosphine is a phosphitylation reagent used for the selective modification of hydroxyl groups. It is primarily employed in organic synthesis and pharmaceutical research as an intermediate for introducing phosphite linkages.

Phosphitylation of hydroxyl groups in unprotected amino acid side chainsReagent for oligonucleotide synthesisLaboratory-scale phosphorylation reagent

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

3-{3-[{[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl}-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one

CAS1086026-31-4

pharmaceutical intermediate

ReferenceSame Category

2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide

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pharmaceutical intermediate

ReferenceSame Category

Tert-Butyl L-alpha-glutaminate--hydrogen chloride (1/1)

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pharmaceutical intermediate

ReferenceSame Category

(3S)-3-Aminopentanoic acid methyl ester

CAS1086106-57-1

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for Bis(benzyloxy)(diisopropylamino)phosphine (CAS 108549-23-1) is 2929.90.

HS code (international, 6-digit)

2929.90

EU CN code (8-digit)

2929 90 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

N-bis(phenylmethoxy)phosphanyl-N-propan-2-ylpropan-2-amine

InChIKey

ANPWLBTUUNFQIO-UHFFFAOYSA-N

SMILES

CC(C)N(C(C)C)P(OCC1=CC=CC=C1)OCC2=CC=CC=C2

Synonyms (12)

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