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Home/Compounds/Other/Adapalene
C28H28O3
412.5 g/mol
OtherWarning

Differin

CAS106685-40-9EC620-513-9
Category
Other
Compound Class
n.a
Primary Use
pharmaceutical intermediate

Differin contains adapalene, a naphthoic acid derivative with anti-inflammatory properties. It is a retinoid-like compound used as a pharmaceutical intermediate in the manufacture of dermatological preparations.

pharmaceutical intermediate for topical acne products

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.81

Mehtyl 6-[3-(1-adamanty)-4-methoxy phenyl]-2-naphthoate

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pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.80

6-(3-(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)-4-methoxyphenyl)naphthalene-2-carboxylic acid

CAS1346599-76-5

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.75

6-[(3-Adamantyl-4-methoxyphenyl)]-2-naphthoic Acid Ethyl Ester

CAS951645-46-8

pharmaceutical raw material

ReferenceSame Category

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Research compound

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chemical weapon

ReferenceSame Category

Ethyl hydrogen glutarate

CAS1070-62-8

research intermediate

ReferenceSame Category

2-amino-5-bromopyridine

CAS1072-97-5

research intermediate

Referencesame scaffold

AHPN

CAS125316-60-1

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Warning
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
Identifiers
IUPAC Name

6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid

InChIKey

LZCDAPDGXCYOEH-UHFFFAOYSA-N

SMILES

COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5

Synonyms (48)
  • Adapalene (JAN/USP/INN)
  • Adapalene Gel USP
  • Adapalene for peak identification, European Pharmacopoeia (EP)
  • Adapalene, European Pharmacopoeia (EP)
  • Adapalene, United States Pharmacopeia (USP)
  • Adapaleno [INN-Spanish]
  • Adapalenum [INN-Latin]
  • 271, CD
  • ADAPALENE [MART.]
  • Adaferin
  • Adapalen
  • Adapalene (Standard)
  • Adapalene - Bio-X trade mark
  • Adapalene CRS
  • Adapalene Gel
  • Adapalene Topical Solution
  • Adapalene, >=98% (HPLC)
  • Adapaleno
  • Adapalenum
  • Adapelene
  • Adaplaene
  • Adaplane
  • CABTREO COMPONENT ADAPALENE
  • Curist Acne Relief
  • Differin
  • Differin (TN)
  • Differin Gel
  • Differine
  • EPIDUO COMPONENT ADAPALENE
  • Effaclar
  • IDP-126 Component Adapalene
  • MD Kit
  • Proactiv MD Adapalene
  • Proactiv MD Kit