C28H28O3
412.5 g/mol
OtherWarning
Differin
CAS106685-40-9EC620-513-9
Category
Other
Compound Class
n.a
Primary Use
pharmaceutical intermediate
Differin contains adapalene, a naphthoic acid derivative with anti-inflammatory properties. It is a retinoid-like compound used as a pharmaceutical intermediate in the manufacture of dermatological preparations.
pharmaceutical intermediate for topical acne products
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.81
Mehtyl 6-[3-(1-adamanty)-4-methoxy phenyl]-2-naphthoate
CAS106685-41-0
pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.80
6-(3-(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)-4-methoxyphenyl)naphthalene-2-carboxylic acid
CAS1346599-76-5
pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.75
6-[(3-Adamantyl-4-methoxyphenyl)]-2-naphthoic Acid Ethyl Ester
CAS951645-46-8
pharmaceutical raw material
ReferenceSame Category
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Research compound
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research intermediate
ReferenceSame Category
2-amino-5-bromopyridine
CAS1072-97-5
research intermediate
Referencesame scaffold
AHPN
CAS125316-60-1
pharmaceutical raw material
Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
Customs Tariff Classification
The international HS code for Differin (CAS 106685-40-9) is 2918.99.
HS code (international, 6-digit)
2918.99
EU CN code (8-digit)
2918 99 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid
InChIKey
LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES
COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5
Synonyms (48)
- Adapalene (JAN/USP/INN)
- Adapalene Gel USP
- Adapalene for peak identification, European Pharmacopoeia (EP)
- Adapalene, European Pharmacopoeia (EP)
- Adapalene, United States Pharmacopeia (USP)
- Adapaleno [INN-Spanish]
- Adapalenum [INN-Latin]
- 271, CD
- ADAPALENE [MART.]
- Adaferin
- Adapalen
- Adapalene (Standard)
- Adapalene - Bio-X trade mark
- Adapalene CRS
- Adapalene Gel
- Adapalene Topical Solution
- Adapalene, >=98% (HPLC)
- Adapaleno
- Adapalenum
- Adapelene
- Adaplaene
- Adaplane
- CABTREO COMPONENT ADAPALENE
- Curist Acne Relief
- Differin
- Differin (TN)
- Differin Gel
- Differine
- EPIDUO COMPONENT ADAPALENE
- Effaclar
- IDP-126 Component Adapalene
- MD Kit
- Proactiv MD Adapalene
- Proactiv MD Kit
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