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Home/Compounds/Research Reagent/Fmoc-N-methyl-D-leucine
C22H25NO4
367.4 g/mol
Research Reagent

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-methyl-D-leucine

CAS103478-63-3EC807-806-9
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound

This compound is an Fmoc-protected N-methyl leucine derivative used as a building block in solid-phase peptide synthesis. It is a research reagent that incorporates a methylated backbone to introduce conformational constraints or enhance metabolic stability in synthetic peptides.

Research reagent for Fmoc-based solid-phase peptide synthesisBuilding block for incorporation of N-methyl-D-leucine into peptide sequences

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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SimilarStructure SimilarSimilarity 0.73

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Identifiers
IUPAC Name

(2R)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]-4-methylpentanoic acid

InChIKey

BUJQSIPFDWLNDC-HXUWFJFHSA-N

SMILES

CC(C)C[C@H](C(=O)O)N(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Synonyms (10)
  • Fmoc-D-MeLeu-OH
  • Fmoc-D-N-Me-Leu-OH
  • Fmoc-N-Me-D-Leu-OH
  • Fmoc-N-methyl-D-leucine
  • Fmoc-Nalpha-methyl-D-leucine