Home/Compounds/Pharmaceutical Intermediate/2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene
C18H14BrFS
361.3 g/mol
Pharmaceutical IntermediateWarning
2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene
CAS1030825-20-7EC807-103-7
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a thiophene derivative used as a pharmaceutical intermediate in the manufacturing of canagliflozin, a sodium-glucose cotransporter-2 inhibitor. It features a brominated methylphenyl group and a fluorophenyl ring attached to a central thiophene core.
Pharmaceutical intermediate for canagliflozin synthesisBuilding block in organic synthesis for SGLT2 inhibitor development
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1030825-20-7
Related Compounds
SimilarStructure SimilarSimilarity 0.72
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Safety Reference
Warning
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
2-[(5-bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene
InChIKey
VLRIERSBZHUCOW-UHFFFAOYSA-N
SMILES
CC1=C(C=C(C=C1)Br)CC2=CC=C(S2)C3=CC=C(C=C3)F
Synonyms (9)
- Canagliflozin INT4
- Canagliflozin Impurity 40
- Canagliflozin intermediate2