ChemAbout

ChemAbout is a B2B platform where chemical buyers and suppliers discover each other.

Post a purchase requestList your products (for suppliers)
© 2026 ChemAbout
Compound Index|Demand Board|Insights|Exhibitions|Compliance|Help Center|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/API/Difelikefalin
C36H53N7O6
679.8 g/mol
API

Difelikefalin

CAS1024828-77-0
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material

Difelikefalin is a synthetic peptide compound that functions as a peripherally-restricted, highly selective agonist of the κ-opioid receptor. It is used as an active pharmaceutical ingredient in the manufacturing of products for the management of moderate to severe itch.

pharmaceutical raw material for antipruritic formulationscompound for κ-opioid receptor research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing Difelikefalin?

Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.

Post a Purchase Request→Supplier? List your product for this CAS→

Related Compounds

StrongSame Parent

Difelikefalin acetate

CAS1024829-44-4

pharmaceutical raw material

ReferenceSame Category

Huperzine A

CAS102518-79-6

pharmaceutical raw material

ReferenceSame Category

Valbenazine

CAS1025504-45-3

pharmaceutical raw material

ReferenceSame Category

Lifitegrast

CAS1025967-78-5

pharmaceutical raw material

ReferenceSame Category

3-(aminomethyl)-5-methylhexanamide

CAS1026009-73-3

pharmaceutical raw material

Related Reading

Therapeutic Peptides in 2026: This Year's Breakthroughs

2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

Read more

Customs Tariff Classification

The international HS code for Difelikefalin (CAS 1024828-77-0) is 2933.39.

HS code (international, 6-digit)

2933.39

EU CN code (8-digit)

2933 39 99

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

4-amino-1-[(2R)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid

InChIKey

FWMNVWWHGCHHJJ-SKKKGAJSSA-N

SMILES

CC(C)C[C@H](C(=O)N[C@H](CCCCN)C(=O)N1CCC(CC1)(C(=O)O)N)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=CC=C3)N

Synonyms (24)
  • Difelikefalin (USAN/INN)
  • 1024828-77-0 (free base)
  • CR-845; FE-202845
  • DIFELIKEFALIN ACETATE
  • Difelikefalin
  • Difelikefalin (CR845)
  • Difelikefalin TFA
  • Kapruvia
  • Korsuva
  • US9359399, 2
  • difelicefalina
  • difelikefaline
  • difelikefalinum

Sourcing Difelikefalin?

Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.

Post a Purchase Request→Supplier? List your product for this CAS→