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Home/Compounds/API/Difelikefalin
C36H53N7O6
679.8 g/mol
API

Difelikefalin

CAS1024828-77-0
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material

Difelikefalin is a synthetic peptide compound that functions as a peripherally-restricted, highly selective agonist of the κ-opioid receptor. It is used as an active pharmaceutical ingredient in the manufacturing of products for the management of moderate to severe itch.

pharmaceutical raw material for antipruritic formulationscompound for κ-opioid receptor research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Difelikefalin acetate

CAS1024829-44-4

pharmaceutical raw material

ReferenceSame Category

Huperzine A

CAS102518-79-6

pharmaceutical raw material

ReferenceSame Category

Valbenazine

CAS1025504-45-3

pharmaceutical raw material

ReferenceSame Category

Lifitegrast

CAS1025967-78-5

pharmaceutical raw material

ReferenceSame Category

3-(aminomethyl)-5-methylhexanamide

CAS1026009-73-3

pharmaceutical raw material

Identifiers
IUPAC Name

4-amino-1-[(2R)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid

InChIKey

FWMNVWWHGCHHJJ-SKKKGAJSSA-N

SMILES

CC(C)C[C@H](C(=O)N[C@H](CCCCN)C(=O)N1CCC(CC1)(C(=O)O)N)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=CC=C3)N

Synonyms (24)
  • Difelikefalin (USAN/INN)
  • 1024828-77-0 (free base)
  • CR-845; FE-202845
  • DIFELIKEFALIN ACETATE
  • Difelikefalin
  • Difelikefalin (CR845)
  • Difelikefalin TFA
  • Kapruvia
  • Korsuva
  • US9359399, 2
  • difelicefalina
  • difelikefaline
  • difelikefalinum