Home/Compounds/Pharmaceutical Intermediate/6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
C13H13BrClN3O
342.62 g/mol
Pharmaceutical IntermediateDanger
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
CAS1016636-76-2
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a brominated and chlorinated pyridopyrimidinone derivative used as a pharmaceutical intermediate in the manufacturing of palbociclib, a drug substance for cancer research.
Pharmaceutical intermediate for palbociclib
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1016636-76-2
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Referencesame scaffold
6-acetyl-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
CAS1651214-73-1
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Referencesame scaffold
2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
CAS1013916-37-4
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Safety Reference
Danger
H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one
InChIKey
HJQCAEDIUJXGCQ-UHFFFAOYSA-N
SMILES
CC1=C(C(=O)N(C2=NC(=NC=C12)Cl)C3CCCC3)Br
Synonyms (9)
- Palbociclib Impurity 25
- palbociclib intermediate