Home/Compounds/Pharmaceutical Intermediate/(2E,4R)-5-[1,1'-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic acid
C23H27NO4
381.5 g/mol
Pharmaceutical Intermediate
(2E,4R)-5-[1,1'-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic acid
CAS1012341-48-8
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate
This compound is a pharmaceutical intermediate specifically used in the manufacturing process of sacubitril. It is a chiral, aromatic-containing carboxylic acid with a tert-butoxycarbonyl protecting group, featuring a biphenyl moiety.
Pharmaceutical intermediate for sacubitril
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.78
(R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate
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Safety Reference
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects
Identifiers
IUPAC Name
(E,4R)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pent-2-enoic acid
InChIKey
JXTNUXJSXXIIFE-VISDOYDDSA-N
SMILES
C/C(=C\[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)OC(C)(C)C)/C(=O)O
Synonyms (13)
- LCZ-696 Impurity 58
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