C15H10N2O2
250.25 g/mol
Industrial ChemicalDanger
4,4'-Diphenylmethane diisocyanate
CAS101-68-8EC202-966-0
Category
Industrial Chemical
Compound Class
Aromatic
Primary Use
Production of polyurethane foams
4,4'-Diphenylmethane diisocyanate is the most widely used isomer of methylene diphenyl diisocyanate (MDI), an aromatic diisocyanate. It is a key industrial chemical primarily employed in the production of polyurethane foams.
Production of polyurethane foams
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Restricted or banned substances
Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.
Relevant lists:EU REACH Restriction List
CAS 101-68-8
Related Compounds
ReferenceSame Category
N-isopropyl-N'-phenyl-1,4-phenylenediamine
CAS101-72-4
Rubber antioxidant and antiozonant
ReferenceSame Category
4,4'-dichlorodiphenylmethane
CAS101-76-8
intermediate in chemical synthesis
ReferenceSame Category
4,4′-methylenedianiline
CAS101-77-9
precursor to polyurethanes
ReferenceSame Category
Diaminodiphenyl ether
CAS101-80-4
Chemical intermediate for polyimide resins
Safety Reference
Danger
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H351Suspected of causing cancer
H373May cause damage to organs through prolonged or repeated exposure
H330Fatal if inhaled
H320Causes eye irritation
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
Customs Tariff Classification
The international HS code for 4,4'-Diphenylmethane diisocyanate (CAS 101-68-8) is 2929.10.
HS code (international, 6-digit)
2929.10
EU CN code (8-digit)
2929 10 00
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
1-isocyanato-4-[(4-isocyanatophenyl)methyl]benzene
InChIKey
UPMLOUAZCHDJJD-UHFFFAOYSA-N
SMILES
C1=CC(=CC=C1CC2=CC=C(C=C2)N=C=O)N=C=O
Synonyms (54)
- MDI
- MDR
- PMDI
- 4,4'-MDI
- Caradate 30
- Crude MDI
- Desmodur 44
- Difenil-metan-diisocianato
- Difenylmethaan-diisocyanaat
- Difenylmethaan-dissocyanaat
- Diphenylmethane diisocyanate
- Diphenylmethyl diisocyanate
- Generic MDI
- Hylene M50
- Isonate
- Isonate 125 MF
- Isonate 125M
- Methylbisphenyl isocyanate
- Nacconate 300
- Nocconate 300
- Non-isomeric-specific MDI
- Pure MDI
- Rubinate 44
- methylenediphenyl