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Home/Compounds/API/Cobicistat
C40H53N7O5S2
776 g/mol
API

Cobicistat

CAS1004316-88-4
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Cobicistat is a pharmaceutical active ingredient used in the manufacturing of medications for HIV infection. It functions by inhibiting human CYP3A proteins, which are involved in drug metabolism.

pharmaceutical raw materialCYP3A inhibitor in HIV therapy manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

1,3-thiazol-5-ylmethyl N-[(2R,5R)-5-[[(2S)-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]-4-morpholin-4-ylbutanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate

InChIKey

ZCIGNRJZKPOIKD-CQXVEOKZSA-N

SMILES

CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](CCN2CCOCC2)C(=O)N[C@H](CC[C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5

Synonyms (32)
  • A1APA
  • COBI
  • Cobicistat (JAN/USAN/INN)
  • 9350, GS
  • COBICISTAT, (R,R,S)-
  • Cobicistat
  • Cobicistat (GS-9350)
  • Cobicistat (Standard)
  • Cobicistat on silicon dioxide
  • EVOTAZ COMPONENT COBICISTAT
  • GENVOYA COMPONENT COBICISTAT
  • REZOLSTA COMPONENT COBICISTAT
  • STRIBILD COMPONENT COBICISTAT
  • SYMTUZA COMPONENT COBICISTAT
  • Tybost
  • Tybost (TN)
  • cobicistatum