C50H58N7O9P
932 g/mol
의약 중간체경고
2'-O-MOE-N6-Benzoyl-Adenosine Phosphoramidite
CAS251647-53-7EC804-906-4
용도 분류
의약 중간체
화합물 분류
아미드
주요 용도
의약 중간체
This compound is a protected nucleoside phosphoramidite building block used in the synthesis of oligonucleotides. It features a 2'-O-(2-methoxyethyl) modification, an N6-benzoyl protected adenine base, and a dimethoxytrityl protecting group.
Nucleoside phosphoramidite building block for oligonucleotide synthesisPharmaceutical intermediate for nucleic acid-based research
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관련 화합물
강한 관련구조 유사유사도 0.91
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
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phosphoramidite monomer for oligonucleotide synthesis
강한 관련구조 유사유사도 0.90
(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
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nucleotide phosphoramidite reagent for oligonucleotide synthesis
강한 관련구조 유사유사도 0.89
(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(hexadecyloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
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Nucleoside phosphoramidite for oligonucleotide synthesis
강한 관련구조 유사유사도 0.87
Bz-rA Phosphoramidite
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Phosphoramidite intermediate for oligonucleotide synthesis
용도 관련동일 용도
N-Benzoyl-5'-O-(bis(4-methoxyphenyl)(phenyl)methyl)-2'-O-(tert-butyl(dimethyl)silyl)adenosine
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nucleoside phosphoramidite building block
용도 관련동일 용도
DMF-dG Phosphoramidite
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nucleoside phosphoramidite building block
용도 관련동일 용도
(2R)-2-(((2R)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)ethyl benzoate
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nucleoside phosphoramidite building block
참고동일 카테고리
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS251647-55-9
protected nucleoside phosphoramidite building block
안전 참조
경고
H302Harmful if swallowed
식별자
IUPAC 이름
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChIKey
VPBYBQBHLYRLHG-HDMAWCRFSA-N
SMILES
CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OCCOC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
동의어 목록 (14)
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