홈/화합물/의약 중간체/DMF-dG Phosphoramidite

C₄₃H₅₃N₈O₇P

824.9 g/mol

의약 중간체

DMF-dG Phosphoramidite

CAS330628-04-1

용도 분류

의약 중간체

화합물 분류

헤테로사이클

주요 용도

의약 중간체

DMF-dG Phosphoramidite is a chemically modified nucleoside building block used in the solid-phase synthesis of oligonucleotides. Its structure incorporates a protected deoxyguanosine base with a dimethylformamidine (DMF) protecting group, a dimethoxytrityl (DMT) group on the 5'-hydroxyl, and a phosphoramidite moiety on the 3'-hydroxyl, enabling automated DNA synthesis.

Nucleoside phosphoramidite building block for oligonucleotide synthesisPharmaceutical intermediate for nucleic acid-based research

콘텐츠 범위: 이 페이지의 정보는 화학물질 식별 및 산업 공급·연구개발·제조 맥락을 대상으로 합니다. 치료 효능 주장, 의료 조언 또는 의약품 사용 지침에 해당하지 않습니다.

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참고동일 카테고리

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Pharmaceutical intermediate

식별자

IUPAC 이름

N'-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

InChIKey

YRQAXTCBMPFGAN-UNHDIWNRSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=C(NC6=O)/N=C/N(C)C

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