홈/화합물/의약 중간체/Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

C₄₇H₆₀N₇O₁₀P

914 g/mol

의약 중간체경고

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS251647-55-9

용도 분류

의약 중간체

화합물 분류

기타

주요 용도

의약 중간체

This compound is a protected nucleoside phosphoramidite building block used primarily in oligonucleotide synthesis. It is a chemically modified guanosine derivative with multiple protecting groups and a phosphoramidite functional group.

Protected building block for oligonucleotide synthesisPharmaceutical intermediate for nucleoside analog production

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CAS 251647-55-9

안전 참조

유해

경고

H302Harmful if swallowed

식별자

IUPAC 이름

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChIKey

LADCDGNEBIQAAU-SBCRAQIVSA-N

SMILES

CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCOC

동의어 목록 (20)

DMT-2'-O-MOE-G(iBu)-CEP
DMT-2M-O-Me-rG(ib) amidite
DMT-2mu-O-Me-rG(ib) amidite
DMT-2|I-O-Me-rG(ib)amidite

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

관련 화합물

안전 참조