SC-VC-PAB-MMAE is a research reagent designed for use in antibody-drug conjugate (ADC) development. It consists of a monomethyl auristatin E (MMAE) payload linked to a cleavable valine-citrulline-p-aminobenzylcarbamate (VC-PAB) spacer and a maleimide functional group for conjugation to antibodies.
Alcance del contenido: La información de esta página se refiere a la identificación química y a los contextos de suministro industrial, investigación y producción. No constituye una afirmación terapéutica, un consejo médico ni instrucciones de uso de medicamentos.
¿Adquiriendo o suministrando este compuesto?
Publique su inventario o una solicitud de compra
CAS 2259318-46-0
SuO-Glu-Val-Cit-PAB-MMAE
antibody-drug conjugate linker payload
VC-PAB-MMAE
antibody-drug conjugate intermediate
MAL-di-EG-Val-Cit-PAB-MMAE
antibody-drug conjugate linker payload
(2E)-3-[1-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-2-cyano-2-propenoic acid
research compound
5-bromo-2,3-dihydro-1H-inden-4-amine
research compound
5-Chloronicotinic acid
research compound
4-cyanobutylzinc bromide
organometallic reagent for cross-coupling
(2,5-dioxopyrrolidin-1-yl) 6-[[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-[[[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-methylcarbamoyl]oxymethyl]anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-6-oxohexanoate
IOJRSUDQDOZEEX-SBEKVBMRSA-N
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)CCCCC(=O)ON4C(=O)CCC4=O