Monomethylauristatin D is a synthetic compound used as a cytotoxic payload in antibody-drug conjugates (ADCs). It is a highly complex, flexible molecule with multiple amide groups, aromatic rings, and ether linkages, designed to disrupt microtubule dynamics in targeted cancer cells.
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CAS 203849-91-6
Dolastatin 10
Anticagent / microtubule inhibitor
Auristatin 0101
Antibody-drug conjugate payload
MMAF
pharmaceutical intermediate
Mc-MMAD
antibody drug conjugate payload
Pexidartinib hydrochloride
active pharmaceutical ingredient
Indibulin
tubulin modulator antineoplastic agent
Tamiflu
active pharmaceutical ingredient
Edotreotide
active pharmaceutical ingredient
(2S)-N-[(2S)-1-[[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamide
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