Auristatin F, specifically its monomethyl derivative monomethyl auristatin F (MMAF), is a synthetic antineoplastic agent. It serves as the payload in antibody-drug conjugates (ADCs), including the approved drug belantamab mafodotin for multiple myeloma and experimental ADCs such as vorsetuzumab mafodotin and SGN-CD19A.
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CAS 163768-50-1
MMAF
pharmaceutical intermediate
Soblidotin
antimitotic agent
L-Valinamide, N,N-dimethyl-L-valyl-N-((1S,2R)-4-((2S)-2-((1R,2R)-3-(((1R,2S)-2-hydro xy-1-methyl-
active pharmaceutical ingredient
MC-MMAF
antibody-drug conjugate payload
(R)-4-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile benzoate
Pharmaceutical intermediate for alogliptin
(S)-Alogliptin Benzoate Salt
active pharmaceutical ingredient
Propoxyphene hydrochloride
opioid analgesic active pharmaceutical ingredient
Valbenazine tosylate
active pharmaceutical ingredient
(2S)-2-[[(2R,3R)-3-[(2S)-1-[(3R,4S,5S)-4-[[(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methoxy-5-methylheptanoyl]pyrrolidin-2-yl]-3-methoxy-2-methylpropanoyl]amino]-3-phenylpropanoic acid
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