This compound is a Fmoc-protected, indole-containing amino acid building block designed for use in solid-phase peptide synthesis. It features a sterically hindered oxazolidine ring that enables orthogonal deprotection strategies during peptide chain assembly.
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CAS 936707-21-0
Fmoc-Trp(Boc)-Ser(Psi(Me,Me)pro)-OH
peptide building block
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-indol-3-yl)propanoic acid
Building block for peptide synthesis
2-{[(tert-butoxy)carbonyl]amino}-3-methoxypropanoic acid
Building block for peptide synthesis
4-Amino-1-Boc-piperidine
Building block for peptide synthesis
8-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione
pharmaceutical intermediate
7-bromopyrrolo[2,1-f][1,2,4]triazin-4-amine
Pharmaceutical intermediate
(E)-N'-(2-cyano-4-(3-(1-hydroxy-2-methylpropan-2-yl)thioureido)phenyl)-N,N-dimethylformimidamide
pharmaceutical intermediate
4-((1,2,4)Triazolo(1,5-a)pyrid-7-yloxy)-3-methylaniline
Pharmaceutical intermediate for Tucatinib
(4S,5R)-3-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoyl]-2,2,5-trimethyl-1,3-oxazolidine-4-carboxylic acid
XCLJOQSZEAUSDT-UBUDTRSQSA-N
C[C@@H]1[C@H](N(C(O1)(C)C)C(=O)[C@H](CC2=CN(C3=CC=CC=C32)C(=O)OC(C)(C)C)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46)C(=O)O
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