This compound is a sulfamoyl-substituted pyrimidine derivative featuring bromophenyl and chloropyrimidinyl ether moieties. It is primarily utilized as a pharmaceutical intermediate in the synthesis of research compounds related to Macitentan analogs.
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CAS 2443747-63-3
Macitentan
active pharmaceutical ingredient
Sulfamide, N-[6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-5-(4-chlorophenyl)-4-pyrimidinyl]-N'-propyl-
pharmaceutical intermediate
Macitentan metabolite M4
Active pharmaceutical ingredient metabolite
Benzyl (2S)-2-amino-6-(phenylmethoxycarbonylamino)hexanoate
Pharmaceutical intermediate
4-Phenyl-1-(p-tolylsulphonyl)piperidine-4-carbonitrile
Pharmaceutical intermediate synthesis
N-boc-5-hydroxyanthranilic acid
Pharmaceutical intermediate for synthesis
4-((4-Chloropyrimidin-2-yl)amino)benzonitrile
Pharmaceutical intermediate
Aprocitentan
pharmaceutical active ingredient
5-(4-bromophenyl)-6-[2-(5-chloropyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine
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CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Cl)C3=CC=C(C=C3)Br