SC-VC-PAB-MMAE is a research reagent designed for use in antibody-drug conjugate (ADC) development. It consists of a monomethyl auristatin E (MMAE) payload linked to a cleavable valine-citrulline-p-aminobenzylcarbamate (VC-PAB) spacer and a maleimide functional group for conjugation to antibodies.
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CAS 2259318-46-0
SuO-Glu-Val-Cit-PAB-MMAE
antibody-drug conjugate linker payload
VC-PAB-MMAE
antibody-drug conjugate intermediate
MAL-di-EG-Val-Cit-PAB-MMAE
antibody-drug conjugate linker payload
(2E)-3-[1-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-2-cyano-2-propenoic acid
research compound
5-bromo-2,3-dihydro-1H-inden-4-amine
research compound
5-Chloronicotinic acid
research compound
4-cyanobutylzinc bromide
organometallic reagent for cross-coupling
(2,5-dioxopyrrolidin-1-yl) 6-[[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-[[[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-methylcarbamoyl]oxymethyl]anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-6-oxohexanoate
IOJRSUDQDOZEEX-SBEKVBMRSA-N
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