This compound is an impurity reference standard for afatinib, a pharmaceutical intermediate. It is specifically designated as Afatinib impurity 12 and is used in analytical testing and quality control during pharmaceutical manufacturing.
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CAS 2121530-37-6
Afatinib Impurity I
pharmaceutical reference standard
N-desmethyl afatinib
Afatinib metabolite and impurity reference standard
(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity)
n.a
Afatinib N-oxide
active pharmaceutical ingredient metabolite
N-[3-Amino-4-(methylamino)benzoyl]-N-2-pyridinyl-Beta-alanine Ethyl Ester
pharmaceutical intermediate
B-(4-Ethoxy-2,3-difluorophenyl)boronic acid
Pharmaceutical intermediate
2-(3-(4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile
pharmaceutical intermediate
Tert-Butyl ((2R,3R)-4-(4-acetamido-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
pharmaceutical intermediate
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-hydroxybut-2-enamide
XZMUSENASPIMAT-YUKKFKLSSA-N
C1COC[C@H]1OC2=C(C=C3C(=C2)N=CN=C3NC4=CC(=C(C=C4)F)Cl)NC(=O)/C=C/CO