C45H57NO14
835.9 g/mol
Ingrediente ativo (API)Perigo
Jevtana
cabazitaxel
CAS183133-96-2
Categoria
Ingrediente ativo (API)
Classe do Composto
Éster
Uso Principal
Matéria-prima farmacêutica
Jevtana is the brand name for cabazitaxel, an active pharmaceutical ingredient used in drug manufacturing. It functions as a microtubule inhibitor and is investigated for antineoplastic activity.
Escopo do conteúdo: As informações desta página dizem respeito à identificação química e aos contextos de fornecimento industrial, pesquisa e produção. Não constituem alegação terapêutica, aconselhamento médico ou instruções de uso de medicamentos.
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CAS 183133-96-2
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((1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-((2R,3S)-2-hydroxy-3-((2-methylpropan-2-yl)oxycarbonylamino)-3-phenylpropanoyl)oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo(11.3.1.03,10.04,7)heptadec-13-en-2-yl) benzoate;propan-2-one
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Referência de Segurança
Perigo
H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Identificadores
Nome IUPAC
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
InChIKey
BMQGVNUXMIRLCK-OAGWZNDDSA-N
SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC
Sinônimos (33)
- EX-A838
- Cabazitaxel (USAN/INN)
- AB01273971-01
- CABAZITAXEL [MART.]
- Cabazitaxel (Jevtana)
- Cabazitaxel (Standard)
- Cabazitaxel Injection
- Cabazitaxelum
- Jevanta
- Jevtana
- Jevtana (TN)
- Jevtana Kit
- RPR-116258A
- TXD 258
- Taxoid XRP6258
- Xrp6258
- cabazitaxel acetonate
- kabazitaxel