C75H101N9O23
1496.6 g/mol
Ingrediente ativo (API)Perigo
Tesirine
CAS1595275-62-9
Categoria
Ingrediente ativo (API)
Classe do Composto
Peptídeo
Uso Principal
Matéria-prima farmacêutica
Tesirine is a chemical compound used as the payload in antibody-drug conjugates (ADCs). It is a component of loncastuximab tesirine, an ADC targeting the CD19 protein for B-cell lymphoma research.
Antibody-drug conjugate payloadPharmaceutical raw material for ADC manufacturing
Escopo do conteúdo: As informações desta página dizem respeito à identificação química e aos contextos de fornecimento industrial, pesquisa e produção. Não constituem alegação terapêutica, aconselhamento médico ou instruções de uso de medicamentos.
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CAS 1595275-62-9
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Referência de Segurança
Perigo
H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
Identificadores
Nome IUPAC
[4-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-methylbutanoyl]amino]propanoyl]amino]phenyl]methyl (6S,6aS)-3-[5-[[(6aS)-2-methoxy-8-methyl-11-oxo-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]pentoxy]-6-hydroxy-2-methoxy-8-methyl-11-oxo-6a,7-dihydro-6H-pyrrolo[2,1-c][1,4]benzodiazepine-5-carboxylate
InChIKey
HKGATZAPXCCEJR-OWRSNIELSA-N
SMILES
CC1=CN2[C@@H](C1)C=NC3=CC(=C(C=C3C2=O)OC)OCCCCCOC4=C(C=C5C(=C4)N([C@H]([C@@H]6CC(=CN6C5=O)C)O)C(=O)OCC7=CC=C(C=C7)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN8C(=O)C=CC8=O)OC
Sinônimos (2)
- MP-PEG8-VA-PABC-PBD Dimer
- Tesirine