C21H29N6O5P
476.5 g/mol
원료의약품위험
TENOFOVIR ALAFENAMIDE
CAS379270-37-8
용도 분류
원료의약품
화합물 분류
아민
주요 용도
의약 원료
Tenofovir alafenamide is a prodrug of tenofovir, a reverse transcriptase inhibitor used in antiviral therapy. It is a phosphoramidate ester derivative formulated for pharmaceutical manufacturing as an active pharmaceutical ingredient.
Active pharmaceutical ingredient in combination therapy for HIV-1 infection
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CAS 379270-37-8
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참고stereoisomer of
Isopropyl ((r)-((((r)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninate
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Nucleotide reverse transcriptase inhibitor prodrug
참고stereoisomer of
Isopropyl ((s)-((((r)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-d-alaninate
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pharmaceutical impurity standard
참고stereoisomer of
Isopropyl ((r)-((((r)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-d-alaninate
CAS2053424-88-5
Pharmaceutical impurity reference standard
안전 참조
위험
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
식별자
IUPAC 이름
propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
InChIKey
LDEKQSIMHVQZJK-CAQYMETFSA-N
SMILES
C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3
동의어 목록 (24)
- Tenofovir alafenamide (USAN/INN)
- GS-7340 Tenofovir alafenamide
- GS-7340?
- TENOFOVIR ALAFENAMIDE
- TFV Alafenamide
- Tenofovir alafenamida
- US12049474, Compound TAF
- Vemlidy