C20H16N2O5
364.4 g/mol
원료의약품경고
10-Hydroxycamptothecin
CAS19685-09-7EC613-598-9
용도 분류
원료의약품
화합물 분류
천연물
주요 용도
의약 원료
10-Hydroxycamptothecin is a pyranoindolizinoquinoline compound under investigation in clinical research. It is a naturally occurring alkaloid found in Nothapodytes nimmoniana, Fusarium solani, and Camptotheca acuminata.
pharmaceutical research compoundactive pharmaceutical ingredient
콘텐츠 범위: 이 페이지의 정보는 화학물질 식별 및 산업 공급·연구개발·제조 맥락을 대상으로 합니다. 치료 효능 주장, 의료 조언 또는 의약품 사용 지침에 해당하지 않습니다.
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CAS 19685-09-7
관련 화합물
유사구조 유사유사도 0.80
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topoisomerase inhibitor
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참고same scaffold
7-Ethyl-10-hydroxycamptothecin
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참고same scaffold
9-Aminocamptothecin
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anticancer active pharmaceutical ingredient
참고same scaffold
TOPOTECAN HYDROCHLORIDE
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active pharmaceutical ingredient
안전 참조
경고
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H340May cause genetic defects
H350May cause cancer
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life
식별자
IUPAC 이름
(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
InChIKey
HAWSQZCWOQZXHI-FQEVSTJZSA-N
SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O
동의어 목록 (22)
- 10-HCPT
- Irinotecan EP Impurity B; Camptothecin 10-Hydroxy Impurity
- (S)-10-Hydroxycamptothecin
- 10-Hydroxy-CPT
- 10-Hydroxycamp-totecin
- 10-Hydroxycamptothecin
- 10-hydroxycamptothecine
- Camptothecin, 10-hydroxy-
- Camptothecin, hydroxy-
- Camptothecine, 10-hydroxy-
- Hydroxycamptothecin
- Hydroxycamptothecine
- ethyl(dihydroxy)[?]dione