C23H24ClN3O5
457.9 g/mol
원료의약품위험
TOPOTECAN HYDROCHLORIDE
CAS119413-54-6
용도 분류
원료의약품
화합물 분류
헤테로사이클
주요 용도
의약 원료
Topotecan hydrochloride is a synthetic, water-soluble analog of camptothecin and functions as a topoisomerase inhibitor. It is used as an active pharmaceutical ingredient in the manufacturing of chemotherapeutic medications.
Active pharmaceutical ingredient for cancer treatment formulations
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CAS 119413-54-6
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안전 참조
위험
H300Fatal if swallowed
H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H370Causes damage to organs
H412Harmful to aquatic life with long lasting effects
식별자
IUPAC 이름
(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
InChIKey
DGHHQBMTXTWTJV-BQAIUKQQSA-N
SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl
동의어 목록 (36)
- Topotecan hydrochloride (USAN)
- Evotopin
- Evotropin
- Hycamptamine hydrochloride
- Hycamtin
- Hycamtin (TN)
- Hycamtin (TN) (GlaxoSmith)
- Hydrochloride, Nogitecan
- Hydrochloride, Topotecan
- Nogitecan hydrochloride
- Nogitecan hydrochloride (JAN)
- Potactasol (TN)
- SK&F S-104864-A
- SKF 104864A
- SKF 104864A; NSC 609669
- TOPOTECAN HYDROCHLORIDE
- Topotecan (as hydrochloride)
- Topotecan Actavis
- Topotecan Hcl
- Topotecan Hospira
- Topotecan Hydrocholoride
- Topotecan monohydrochloride
- Topotecan teva
- potactasol