This compound is a modified nucleoside derivative used as a pharmaceutical intermediate in the manufacturing of oligonucleotides. It features a dimethoxytrityl protecting group and a 2-methoxyethoxy modification on the ribose sugar, as indicated by its structure and stereochemistry.
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CAS 163759-50-0
3-Nitro-1-(2,4,6-trimethylbenzene-1-sulfonyl)-1H-1,2,4-triazole
Pharmaceutical intermediate for oligonucleotide synthesis
N4-Ac-C-(S)-GNA phosphoramidite
Pharmaceutical intermediate for oligonucleotide synthesis
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]purin-6-yl]benzamide
Pharmaceutical intermediate for oligonucleotide synthesis
N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
Pharmaceutical intermediate for oligonucleotide synthesis
N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-((2-cyanoethoxy)(diisopropylamino)phosphino)-2'-O-(2-methoxyethyl)-5-methylcytidine
Phosphoramidite for oligonucleotide synthesis
5'-O-DMT-2'-(2-methoxyethyl)uridine 3'-CE phosphoramidite
Oligonucleotide building block
(R)-1-Boc-3-methylpiperazine
pharmaceutical intermediate
(S)-2,4,5-Trifluoro-N-(1,1,1-trifluoropropan-2-yl)benzamide
Pharmaceutical intermediate
1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
WIPCVBQXKBWNRC-PBAMLIMUSA-N
CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OCCOC
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