This compound is a protected 2'-deoxyguanosine derivative used as a building block in the solid-phase chemical synthesis of oligonucleotides. It features a 5'-O-DMTr protecting group and an isobutyryl (iBu) group on the guanine base, along with a 2'-fluoro substitution, which enhances stability for research and manufacturing applications.
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CAS 144089-96-3
5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine
modified nucleoside for oligonucleotide synthesis
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine
nucleoside analog pharmaceutical intermediate
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
protected guanosine for oligonucleotide synthesis
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-
Protected nucleotide building block for oligonucleotide synthesis
5'-DMT-PseudoUridine
Pharmaceutical intermediate for oligonucleotide synthesis
1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
Pharmaceutical intermediate for oligonucleotide synthesis
N-[9-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]-6-oxo-1H-purin-2-yl]-2-phenylacetamide
Pharmaceutical intermediate for oligonucleotide synthesis
N4-Ac-C-(S)-GNA phosphoramidite
Pharmaceutical intermediate for oligonucleotide synthesis
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
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