C32H47F5O3S
606.8 g/mol
Principio activo (API)Peligro
Fulvestrant
Fulvestrant
CAS129453-61-8EC642-998-6
Categoría
Principio activo (API)
Clase de Compuesto
Esteroide
Uso Principal
Materia prima farmacéutica
Fulvestrant is a steroidal compound derived from 17beta-estradiol, modified with a nonyl group and a pentafluoropentylsulfinyl substituent. It functions as an estrogen receptor antagonist and is used in pharmaceutical manufacturing as an active pharmaceutical ingredient.
Pharmaceutical raw material for hormone-sensitive breast cancer therapiesEstrogen receptor antagonist compound
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CAS 129453-61-8
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Referencia de Seguridad
Peligro
H302Harmful if swallowed
H319Causes serious eye irritation
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life
Identificadores
Nombre IUPAC
(7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
InChIKey
VWUXBMIQPBEWFH-WCCTWKNTSA-N
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F
Sinónimos (47)
- Fulvestrant (JAN/USP/INN)
- Fulvestrant for system suitability, European Pharmacopoeia (EP)
- Fulvestrant, European Pharmacopoeia (EP)
- Fulvestrant, United States Pharmacopeia (USP)
- FULVESTRANT [MART.]
- Faslodex
- Faslodex (TN)
- Faslodex(ICI 182,780)
- Fluvestrant
- Fulvestrant
- Fulvestrant (Faslodex)
- Fulvestrant (Standard)
- Fulvestrant CRS
- Fulvestrant R enantiomer
- Fulvestrant S enantiomer
- Fulvestrant, >98% (HPLC)
- ICI 182,780
- ICI 182,780 (Fulvestrant)
- fulvestrantum