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首页/化合物/医药原料药/Etretinate
C23H30O3
354.5 g/mol
医药原料药危险

Etretinate

CAS54350-48-0EC259-119-3
用途分类
医药原料药
化合物类别
酯
主要用途
医药原料

Etretinate is a second-generation retinoid that was used as an active pharmaceutical ingredient in medications for severe psoriasis. It was developed by Hoffmann–La Roche and approved by the FDA in 1986, but later withdrawn from several markets due to a high risk of birth defects.

pharmaceutical raw material for retinoid-based formulationsreference standard in analytical research

内容范围: 本页信息面向化学品识别与工业供应、研发、生产场景,不构成疗效宣称、医疗建议或药品使用指导。

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医药中间体

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相似参考结构相似相似度 0.75

Acitretin Impurity 10

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安全参考

有害
有害
健康危害
健康危害
环境危害
环境危害
危险
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
标识符
IUPAC 名称

ethyl (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate

InChIKey

HQMNCQVAMBCHCO-DJRRULDNSA-N

SMILES

CCOC(=O)/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C(=C(C=C1C)OC)C)C

别名列表 (35)
  • Acitretin EP Impurity B; Etretinate
  • Etretinate (JAN/USAN/INN)
  • Etretinato [INN-Spanish]
  • Etretinatum [INN-Latin]
  • ACITRETIN IMPURITY B
  • B10 9359
  • ETRETINATE [MART.]
  • Ethyl etrinoate
  • Etretinate (Standard)
  • Etretinato
  • Etretinatum
  • Etrinoate, Ethyl
  • Retinoid
  • Ro 10-9359
  • TEGISON (TN)
  • Tegison
  • Tigason
  • Tigazon
  • etretinate