C23H24ClN3O5
457.9 g/mol
医药原料药危险
TOPOTECAN HYDROCHLORIDE
CAS119413-54-6
用途分类
医药原料药
化合物类别
杂环
主要用途
医药原料
盐酸拓扑替康是一种合成的、水溶性的喜树碱类似物，作为拓扑异构酶抑制剂使用。它是一种用于制造化疗药物的活性药物成分。
用于癌症治疗制剂的活性药物成分
内容范围: 本页信息面向化学品识别与工业供应、研发、生产场景，不构成疗效宣称、医疗建议或药品使用指导。
正在采购或供应此化合物？
发布库存产品或采购需求
CAS 119413-54-6
相关化合物
强相关同母体
托普樂肯
CAS123948-87-8
医药原料
相似参考结构相似相似度 0.79
Chimmitecan
CAS185425-25-6
antineoplastic agent
参考同类别
Galanin
CAS119418-04-1
医药原料
参考同类别
呋喹替尼
CAS1194506-26-7
医药原料
参考同类别
Danofloxacin mesylate
CAS119478-55-6
医药原料
参考同类别
Meropenem trihydrate
CAS119478-56-7
医药原料
参考same scaffold
10-羟基喜树碱
CAS19685-09-7
医药原料
参考same scaffold
9-Aminocamptothecin
CAS91421-43-1
医药原料
安全参考
危险
H300Fatal if swallowed
H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H370Causes damage to organs
H412Harmful to aquatic life with long lasting effects
标识符
IUPAC 名称
(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
InChIKey
DGHHQBMTXTWTJV-BQAIUKQQSA-N
SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl
别名列表 (36)
- Topotecan hydrochloride (USAN)
- Evotopin
- Evotropin
- Hycamptamine hydrochloride
- Hycamtin
- Hycamtin (TN)
- Hycamtin (TN) (GlaxoSmith)
- Hydrochloride, Nogitecan
- Hydrochloride, Topotecan
- Nogitecan hydrochloride
- Nogitecan hydrochloride (JAN)
- Potactasol (TN)
- SK&F S-104864-A
- SKF 104864A
- SKF 104864A; NSC 609669
- TOPOTECAN HYDROCHLORIDE
- Topotecan (as hydrochloride)
- Topotecan Actavis
- Topotecan Hcl
- Topotecan Hospira
- Topotecan Hydrocholoride
- Topotecan monohydrochloride
- Topotecan teva
- potactasol