This compound is a phosphoramidite building block used in the solid-phase synthesis of oligonucleotides. It features a protected guanosine nucleoside linked to a cyanoethyl phosphoramidite group, along with a dimethoxytrityl (DMT) protecting group, facilitating automated DNA/RNA synthesis.
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CAS 709641-79-2
(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
Oligonucleotide synthesis phosphoramidite building block
Methyl 16-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-2-(2,4-dioxopyrimidin-1-yl)tetrahydrofuran-3-yl]oxyhexadecanoate
phosphoramidite building block for oligonucleotide synthesis
5'-ODMT cEt m5U Phosphoramidite (Amidite)
phosphoramidite building block for oligonucleotide synthesis
2'-O-Propargyl g(iBu)-3'-phosphoramidite
phosphoramidite building block for oligonucleotide synthesis
N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine 3'-CED
phosphoramidite building block for oligonucleotide synthesis
4-Nitro-2-phenoxyphenol
pharmaceutical intermediate
(2S)-2-(phenoxymethyl)oxirane
Pharmaceutical intermediate
Tricyclo(3.3.1.13,7)decane-1-carboxylic acid, methyl ester
pharmaceutical intermediate
N'-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide
ACJXYPZQPQPGNE-KPKUBJDASA-N
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@@H](O[C@]1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=NC7=C6N=C(NC7=O)N=CN(C)C
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