C62H111N11O12
1202.6 g/mol
Aktif Farmasötik İngredientTehlike
Cyclosporin A
siklosporin
CAS59865-13-3EC611-907-1
Kategori
Aktif Farmasötik İngredient
Bileşik Sınıfı
Peptit
Birincil Kullanım
Farmasötik ham madde
Cyclosporin A is a cyclic peptide compound produced by the fungus Tolypocladium inflatum. It is an active pharmaceutical ingredient primarily used as an immunosuppressant, acting mainly against T-lymphocytes to inhibit cell-mediated immunity.
Organ transplantationControl of immune-mediated dermatological diseases in veterinary use
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CAS 59865-13-3
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Referansstereoisomer of
30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
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active pharmaceutical ingredient
Güvenlik Referansı
Tehlike
H302Harmful if swallowed
H350May cause cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H362May cause harm to breast-fed children
H370Causes damage to organs
Tanımlayıcılar
IUPAC Adı
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
InChIKey
PMATZTZNYRCHOR-CGLBZJNRSA-N
SMILES
CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
Eş Anlamlılar (121)
- CEQUA
- CSA
- CYA
- VEVYE
- Ciclosporin for system suitability, European Pharmacopoeia (EP)
- Ciclosporin, European Pharmacopoeia (EP)
- Ciclosporina [INN-Spanish]
- Ciclosporine [INN-French]
- Ciclosporinum [INN-Latin]
- Cyclosporine, United States Pharmacopeia (USP)
- ,32-undecaone
- 1c5f
- 1cyn
- 2wfj
- 2z6w
- 4jjm
- ANTIBIOTIC S-7481F1
- Abrammune
- Arpimune ME
- Atopica
- Atopica for Cats
- CB-01-09 MMX
- CICLOSPORIN [MART.]
- Capimune
- Capsorin
- CicloMulsion
- Cicloral (antibiotic)
- Ciclosporin
- Ciclosporin CRS
- Ciclosporin DT
- Ciclosporina
- Ciclosporina Germed
- Ciclosporine
- Ciclosporinum
- Cipol N
- Consupren
- Consupren S
- CsA & IFN.alpha.
- CsANeoral
- CyA NOF
- Cyclavance
- CycloSPORINE, Modfied
- Cyclokat
- Cyclorin;
- Cyclosporin
- Cyclosporin A & IFN.alpha.
- Cyclosporin A (Standard)
- Cyclosporin A, >=98.5% (TLC)
- Cyclosporin A, VETRANAL(TM)
- Cyclosporine A
- Cyclosporine Modified
- Cyclosporine manufacturer
- Cyclosporine microemulsion
- Cyclosporine/Chondroitin PF
- Cyclosporine;Ciclosporin
- Deximune
- Equoral
- Gengraf
- Ikervis
- Imusporin
- Mitogard
- Modulis for Cats
- Modulis for Dogs
- Modusik-A
- Neoplanta
- Neoral
- NeuroSTAT
- OL 27-400
- Optimmune
- Optimmune Ophthalmic
- Papilock
- Papilock Mini
- Pulminiq
- Ramihyphin A
- Restasis
- Restasis MultiDose
- S 7481F1
- S-Neoral
- SDZ-OXL 400
- Sandimmun
- Sandimmun Neoral
- Sandimmune
- Sandimmune Neoral
- Sang 35
- SangCyA
- Seciera
- Sigmasporin
- Sigmasporin Microoral
- Sporimune
- Vanquoral
- Vekacia
- Zinograf ME
- Zyclorin
- cyclosporin A
- cyclosporine