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Ana Sayfa/Bileşikler/Aktif Farmasötik İngredient/(D-His2)-Leuprolide Trifluoroacetic Acid Salt
C59H84N16O12
1209.4 g/mol
Aktif Farmasötik İngredient

(D-His2)-Leuprolide Trifluoroacetic Acid Salt

CAS112642-11-2
Kategori
Aktif Farmasötik İngredient
Bileşik Sınıfı
Peptit
Birincil Kullanım
Farmasötik ham madde

(D-His2)-Leuprolide Trifluoroacetic Acid Salt is a peptide-based compound used as an active pharmaceutical ingredient in pharmaceutical manufacturing. It is a modified form of leuprolide, featuring a D-histidine substitution at position 2, and is supplied as a trifluoroacetic acid salt.

pharmaceutical raw materialcompound for peptide-based pharmaceutical manufacturing

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CAS 112642-11-2

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Referansstereoisomer of

(2S)-N-((2R)-1-(((2S)-1-(((2R)-1-(((2S)-1-(((2R)-1-(((2S)-1-(((2S)-5-(diaminomethylideneamino)-1-((2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl)-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)amino)-3-hydroxy-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)-5-oxopyrrolidine-2-carboxamide

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(Des-Gly10,D-Trp3,D-Leu6,Pro-NHEt9)-LHRH Trifluoroacetate

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LHRH analog active pharmaceutical ingredient

Tanımlayıcılar
IUPAC Adı

(2S)-N-[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

InChIKey

GFIJNRVAKGFPGQ-JFMQHNAUSA-N

SMILES

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6

Eş Anlamlılar (9)
  • Leuprolide(Leuprorelin) EP Impurity B
  • D-HIS-LEUPROLIDE
  • Leuprorelin impurity 37
  • pE-(dH)WSY(dL)LRP-NHEt