2'-propargyl U amidite is a phosphoramidite building block used in solid-phase RNA synthesis. Its structure includes a 2'-O-propargyl modification and a dimethoxytrityl (DMT) protecting group, making it suitable for incorporating modified uridine residues into synthetic oligonucleotides.
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CAS 171486-62-7
5'-O-DMT-2'-(2-methoxyethyl)uridine 3'-CE phosphoramidite
Oligonucleotide building block
DMTr-2'-O-C22-rU-3'-CE-Phosphoramidite
Modified uridine phosphoramidite for oligonucleotide synthesis
3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-fluorooxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
modified nucleotide synthesis intermediate
RU Phosphoramidite
RNA oligonucleotide synthesis building block
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
RNA synthesis phosphoramidite building block
Chloropretadalafil
pharmaceutical intermediate
8-Bromo-2'-benzamido-2'-deoxy-Adenosine
adenosine impurity reference standard
Ethyl 4-oxocyclohexanecarboxylate
Pharmaceutical intermediate for drug synthesis
3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-prop-2-ynoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
SKUHDLBLPLSZJC-CYSIDSPMSA-N
CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OCC#C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC